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6. Minglin Ma, Long-Hai Wang, Alexander Ulrich Ernst. Implantable Cell Encapsulation Systems. US Patent No. US20240207486A1. 2024-06-27

5. Long-Hai Wang, Alexander Ulrich Ernst, Minglin Ma, James Arthur Flanders. Methods and devices for providing oxygen to encapsulated cells. US Patent No. US20240024089A1. 2024-01-25

4. Minglin Ma, Long-Hai Wang, Alexander Ulrich Ernst. Implantable Cell Encapsulation Systems. WIPO (PCT) Patent No. WO2022221522A1. 2022-10-20

3. Long-Hai Wang, Alexander Ulrich Ernst, Minglin Ma, James Arthur Flanders. Methods and Devices for Providing Oxygen to Encapsulated Cells. WIPO (PCT) Patent No. WO2022125795A1. 2022-6-16

2. Wanjun Liu, Minglin Ma, James A. Flanders, Long-Hai Wang, Daniel T. Bowers, Qingsheng Liu. Nanofiber-enabled encapsulation devices and uses thereof. WIPO (PCT) Patent No. WO2021202945A1. 2021-10-7

1. Duo An, Long-Hai Wang, Alexander Ulrich Ernst, James Arthur Flanders, Minglin Ma; An atmosphere-breathing refillable biphasic device for cell replacement therapy. US Patent No. US20210170072A1. 2021-06-10

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62. Wei-Qiang Huang, Wei You, Ya-Qi Zhu, Fan Gao, Zhi-Zhi Wu, Guang Chen*, Jun Xiao*, Qi Shao, Long-Hai Wang*, Xuan Nie, Ze Zhang, Chun-Yan Hong* and Ye-Zi You*, Autophagosomes coated in situ with nanodots act as personalised cancer vaccines. Nature Nanotechnology, accepted

61. Wei Huang, Xuan Nie, Xiao-Hong Zhou, Lei Qiao, Hong-Jie Gao, Jing Zang, Long-Kang Yu, Long-Hai Wang*, Ye-Zi You, Phosphatidylserine-targeting bis(zinc-dipicolylamine) farnesol inhibits ATP production in cancer cells to overcome multidrug resistance. Supramolecular Materials, 3, 100068  (2024).

60. Long-Hai Wang^#, Braulio A. Marfil-Garza^#, Alexander U. Ernst, Rena L. Pawlick, Andrew R. Pepper, Kento Okada, Boris Epel, Navin Viswakarma, Mrignayani Kotecha, James Arthur Flanders, Ashim K. Datta, Hong-Jie Gao, Ye-Zi You, Minglin Ma^*, A.M. James Shapiro^*, Inflammation-induced neovascularization of the subcutaneous tissue for the long-term survival of encapsulated islets without immunosuppression. Nature Biomedical Engineering, 8, 1266–1284  (2024). 【Featured on Research Briefing page】

59. Mrignayani Kotecha*, Long-Hai Wang, Safa Hameed, Navin Viswakarma, Minglin Ma, Cherie Stabler, Corinne A. Hoesli, Boris Epel, In vitro oxygen imaging of acellular and cell-loaded beta cell replacement devices. Scientific Reports 13, 15641 (2023).

58. Xuan Nie, Wei You, Ze Zhang, Fan Gao, Xiao-Hong Zhou, Hai-Li Wang, Long-Hai Wang, Guang Chen, Chang-Hui Wang, Chun-Yan Hong, Qi Shao, Fei Wang, Lei Xia, Yang Li, Ye-Zi You*, DPA-Zinc around Polyplexes Acts Like PEG to Reduce Protein Binding while Targeting Cancer Cells. Advanced Healthcare Materials 12, 2203252 (2023).

57. Ze Zhang, Yu Xiong, Peng Yang, Yang Li*, Rui Tang, Xuan Nie, Guang Chen, Long-Hai Wang*, Chun-Yan Hong*, Ye-Zi You*, Easy access to diverse multiblock copolymers with on‐demand blocks via thioester‐relayed in‐chain cascade copolymerization. Angewandte Chemie International Edition 135, e202216685 (2023).

,56. Haili Wang, Wei You, Fan Gao, Lei Zhang, Aizong Shen, Fei Wang*, Guang Chen*, Xuan Nie*, Lei Xia, Wei-Qiang Huang, Wen-Jian Zhang, Long-Hai Wang, Chun-Yan Hong*, Ze Zhang, Ye-Zi You*，Direct cytosolic delivery of DNA by creating fast closable holes in the cell membrane. Chemical Engineering Journal 455, 140962 (2023).

55. Chen Zhang, Dan Yang, Tai-Bao Wang, Xuan Nie, Guang Chen, Long-Hai Wang, Ye-Zi You*, Qin Wang*, Biodegradable hydrogels with photodynamic antibacterial activity promote wound healing and mitigate scar formation. Biomaterials Science 11, 288-297 (2023).

54. Alexander Ulrich Ernst, Long-Hai Wang*, Scott C. Worland, Braulio A. Marfil-Garza, Xi Wang, Wanjun Liu, Alan Chiu, Tatsuya Kin, Doug O’Gorman, Scott Steinschneider, Ashim K. Datta, Klearchos K. Papas, A. M. James Shapiro, Minglin Ma*, A predictive computational platform for optimizing the design of bioartificial pancreas devices. Nature Communications 13, 6031 (2022).

53. Xuan Nie, Fan Gao, Wei You, Guang Chen*, Qi Shao, Long-Hai Wang, Wei-Qiang Huang, Lei Xia*, Ze Zhang, Chun-Yan Hong*, Ye-Zi You*, Caging Pyrophosphate Structure Blocks the Cell Wall Synthesis to Kill Bacteria without Detectable Resistance. Chemical Engineering Journal 450, 138373 (2022).

52. Daqian Gao, Alexander U. Ernst, Xi Wang, Long-Hai Wang, Wanjun Liu*, Minglin Ma*, Engineering A Hierarchical Biphasic Gel For Subcutaneous Vascularization. Advanced Healthcare Materials 11, 2200922, (2022).

51. Wei-Qiang Huang, Ya-Qi Zhu, Wei You, Jing Chen, Fan Gao, Xuan Nie, Ze Zhang, Guang Chen*, Yue Yu*, Lei Xia, Chun-Yan Hong*, Long-Hai Wang, Zong-Yao Hao*, Ye-Zi You*, Tumor Microenvironment Triggered the In Situ Synthesis of an Excellent Sonosensitizer in Tumor for Sonodynamic Therapy. ACS Applied Materials & Interfaces 14, 26469–26479 (2022).

50. Wanjun Liu, James A Flanders, Long‐Hai Wang, Qingsheng Liu, Daniel T Bowers, Kai Wang, Alan Chiu, Xi Wang, Alexander U Ernst, Kaavian Shariati, Julia S Caserto, Benjamin Parker, Daqian Gao, Mitchell D Plesser, Lars G Grunnet, Claude Rescan, Rodrigo Pimentel Carletto, Louise Winkel, Juan M Melero‐Martin, Minglin Ma*, A Safe, Fibrosis‐Mitigating, and Scalable Encapsulation Device Supports Long‐Term Function of Insulin‐Producing Cells. Small 18, 2104899 (2022).

49. Xi Wang, Kristina G Maxwell, Kai Wang, Daniel T Bowers, James A Flanders, Wanjun Liu, Long-Hai Wang, Qingsheng Liu, Chengyang Liu, Ali Naji, Yong Wang, Bo Wang, Jing Chen, Alexander U Ernst, Juan M Melero-Martin, Jeffrey R Millman*, Minglin Ma*, A nanofibrous encapsulation device for safe delivery of insulin-producing cells to treat type 1 diabetes. Science Translational Medicine 13, eabb4601 (2021).

48. Long-Hai Wang, Ye-Zi You*, “High DNA-Binding Affinity and Gene-Transfection Efficacy of Bioreducible Cationic Nanomicelles” in Biomaterial Engineering: Gene Delivery (Springer, 2021), vol. 4, pp. 1-15.

47. Long-Hai Wang, Alexander Ulrich Ernst, James Arthur Flanders, Wanjun Liu, Xi Wang, Ashim K Datta, Boris Epel, Mrignayani Kotecha, Klearchos K Papas, Minglin Ma*, An inverse-breathing encapsulation system for cell delivery. Science Advances 7, eabd5835 (2021).

46. Long-Hai Wang, Alexander Ulrich Ernst, Duo An, Ashim Kumar Datta, Boris Epel, Mrignayani Kotecha, Minglin Ma*, A bioinspired scaffold for rapid oxygenation of cell encapsulation systems. Nature Communications 12, 5846 (2021).

45. Haili Wang, Xuan Nie, Wei You, Weiqiang Huang, Guang Chen, Fan Gao, Lei Xia, Lei Zhang*, Long-Hai Wang, Ai-Zong Shen*, Kai-Le Wu*, Sheng-Gang Ding, Ye-Zi You*, Tug-of-War between Covalent Binding and Electrostatic Interaction Effectively Killing E. coli without Detectable Resistance. ACS Applied Materials & Interfaces 13, 56838-56849 (2021).

44. Wanjun Liu, Minglin Ma, James Flander, Long-Hai Wang, Daniel Bowers, Qingsheng Liu. Nanofiber-enabled encapsulation devices and uses thereof. (WO Patent WO2021202945A1, 2021).

43. Qingsheng Liu#, Yidan Zhang#, Wanjun Liu, Long‐Hai Wang, Young W Choi, Megan Fulton, Stephanie Fuchs, Kaavian Shariati, Mingyu Qiao, Victorien Bernat, Minglin Ma*, A Broad‐Spectrum Antimicrobial and Antiviral Membrane Inactivates SARS‐CoV‐2 in Minutes. Advanced Functional Materials 31, 2103477 (2021).

42. Qingsheng Liu#, Xi Wang#, Alan Chiu, Wanjun Liu, Stephanie Fuchs, Bo Wang, Long‐Hai Wang, James Flanders, Yidan Zhang, Kai Wang, Juan M Melero‐Martin, Minglin Ma*, A Zwitterionic Polyurethane Nanoporous Device with Low Foreign‐Body Response for Islet Encapsulation. Advanced Materials 33, 2102852 (2021).

41. Wei-Qiang Huang, Fei Wang, Ai-Zong Shen*, Lei Zhang, Xuan Nie, Ze Zhang*, Guang Chen, Lei Xia, Long-Hai Wang, Sheng-Gang Ding*, Qing-Yong Meng, Wen-Jian Zhang, Chun-Yan Hong*, Ye-Zi You*, Single nanosheet can sustainably generate oxygen and inhibit respiration simultaneously in cancer cells. Materials Horizons 8, 645-645 (2021).

40. Guang Chen, Zidan Zhang, Wenjian Zhang, Lei Xia, Xuan Nie, Weiqiang Huang, Xiaoqian Wang, Long-Hai Wang*, Chunyan Hong*, Ze Zhang*, Yezi You*, Photopolymerization performed under dark conditions using long-stored electrons in carbon nitride. Materials Horizons 8, 2018-2024 (2021).

39. Duo An, Long-Hai Wang, Alexander Ulrich Ernst, James Flanders, Minglin Ma*. Atmosphere-breathing refillable biphasic device for cell replacement therapy. (US Patent US20210170072A1, 2021).

38. Ze Zhang, Xuan Nie, Fei Wang, Guang Chen, Wei-Qiang Huang, Lei Xia, Wen-Jian Zhang, Zong-Yao Hao*, Chun-Yan Hong*, Long-Hai Wang*, Yezi You*, Rhodanine-based Knoevenagel reaction and ring-opening polymerization for efficiently constructing multicyclic polymers. Nature communications 11, 3654 (2020).

37. Qingsheng Liu, Alan Chiu, Long-Hai Wang, Duo An, Wenchen Li, Esther Y Chen, Yu Zhang, Yehudah Pardo, Sean P McDonough, Lingyun Liu, Wendy F Liu, Jing Chen, Minglin Ma*, Developing mechanically robust, triazole-zwitterionic hydrogels to mitigate foreign body response (FBR) for islet encapsulation. Biomaterials 230, 119640 (2020).

36. Wei-Qiang Huang, Fei Wang, Ai-Zong Shen*, Lei Zhang, Xuan Nie, Ze Zhang*, Guang Chen, Lei Xia, Long-Hai Wang, Sheng-Gang Ding*, Qing-Yong Meng, Wen-Jian Zhang, Chun-Yan Hong*, Ye-Zi You*, Single nanosheet can sustainably generate oxygen and inhibit respiration simultaneously in cancer cells. Materials Horizons 8, 645-645 (2021).

35. Fan Gao, Fei Wang, Xuan Nie, Ze Zhang, Guang Chen, Lei Xia, Long-Hai Wang, Chang-Hui Wang*, Zong-Yao Hao*, Wen-Jian Zhang, Chun-Yan Hong, Ye-Zi You*, Mitochondria-targeted delivery and light controlled release of iron prodrug and CO to enhance cancer therapy by ferroptosis. New Journal of Chemistry 44, 3478-3486 (2020).

34. Stephanie Fuchs, Alexander U Ernst, Long-Hai Wang, Kaavian Shariati, Xi Wang, Qingsheng Liu*, Minglin Ma*, Hydrogels in emerging technologies for type 1 diabetes. Chemical Reviews 121, 11458-11526 (2020).

33. Jing Chen, Dong Wang, Long‐Hai Wang, Wanjun Liu, Alan Chiu, Kaavian Shariati, Qingsheng Liu, Xi Wang, Zhe Zhong, James Webb, Robert E Schwartz, Nikolaos Bouklas, Minglin Ma*, An adhesive hydrogel with “Load‐Sharing” effect as tissue bandages for drug and cell delivery. Advanced Materials 32, 2001628 (2020).

32. Haili Wang, Shenggang Ding*, Ze Zhang, Long-Hai Wang*, Yezi You*, Cationic micelle: A promising nanocarrier for gene delivery with high transfection efficiency. The Journal of Gene Medicine 21, e3101 (2019).

31. Wei Song, Alan Chiu, Long-Hai Wang, Robert E Schwartz, Bin Li, Nikolaos Bouklas, Daniel T Bowers, Duo An, Soon Hon Cheong, James A Flanders, Yehudah Pardo, Qingsheng Liu, Xi Wang, Vivian K Lee, Guohao Dai, Minglin Ma*, Engineering transferrable microvascular meshes for subcutaneous islet transplantation. Nature Communications 10, 4602 (2019).

30. Xuan Nie, Lei Xia, Hai-Li Wang, Guang Chen, Bin Wu, Tian-You Zeng, Chun-Yan Hong*, Long-Hai Wang*, Ye-Zi You*, Photothermal therapy nanomaterials boosting transformation of Fe (III) into Fe (II) in tumor cells for highly improving chemodynamic therapy. ACS Applied Materials & Interfaces 11, 31735-31742 (2019).

29. Yen-Chun Lu*, Tinyi Chu, Matthew S Hall, Dah-Jiun Fu, Quanming Shi, Alan Chiu, Duo An, Long-Hai Wang, Yehudah Pardo, Teresa Southard, Charles G Danko, Jan Liphardt, Alexander Yu Nikitin, Mingming Wu, Claudia Fischbach, Scott Coonrod*, Minglin Ma*, Physical confinement induces malignant transformation in mammary epithelial cells. Biomaterials 217, 119307 (2019).

28. Qingsheng Liu, Alan Chiu, Long-Hai Wang, Duo An, Monica Zhong, Alexandra M Smink, Bart J de Haan, Paul de Vos, Kevin Keane, Andreas Vegge, Esther Y Chen, Wei Song, Wendy F Liu, James Flanders, Claude Rescan, Lars Groth Grunnet, Xi Wang, Minglin Ma*, Zwitterionically modified alginates mitigate cellular overgrowth for cell encapsulation. Nature Communications 10, 5262 (2019).

27. Wei-Qiang Huang, Fei Wang*, Xuan Nie, Ze Zhang, Guang Chen, Lei Xia, Long-Hai Wang, Shen-Gang Ding*, Zong-Yao Hao*, Wen-Jian Zhang, Chun-Yan Hong, Ye-Zi You*, Stable black phosphorus nanosheets exhibiting high tumor-accumulating and mitochondria-targeting for efficient photothermal therapy via double functionalization. ACS Applied Bio Materials 3, 1176-1186 (2019).

26. Alexander U Ernst#, Long‐Hai Wang#, Minglin Ma*, Interconnected toroidal hydrogels for islet encapsulation. Advanced Healthcare Materials 8, 1900423 (2019).

25. Alexander U Ernst#, Daniel T Bowers#, Long-Hai Wang, Kaavian Shariati, Mitchell D Plesser, Natalie K Brown, Tigran Mehrabyan, Minglin Ma*, Nanotechnology in cell replacement therapies for type 1 diabetes. Advanced Drug Delivery Reviews 139, 116-138 (2019).

24. Daniel T Bowers, Wei Song, Long-Hai Wang, Minglin Ma*, Engineering the vasculature for islet transplantation. Acta Biomaterialia 95, 131-151 (2019).

23. Duo An#, Long‐Hai Wang#, Alexander Ulrich Ernst, Alan Chiu, Yen‐Chun Lu, James Arthur Flanders, Ashim Kumar Datta, Minglin Ma*, An Atmosphere‐Breathing Refillable Biphasic Device for Cell Replacement Therapy. Advanced Materials 31, 1905135 (2019).

22. Yu Zhang, You Yong, Duo An, Wei Song, Qingsheng Liu, Long-Hai Wang, Yehudah Pardo, Vanessa R Kern, Paul H Steen, Wei Hong, Zheng Liu, Minglin Ma*, A drip-crosslinked tough hydrogel. Polymer 135, 327-330 (2018).

21. Alexander Ulrich Ernst, Long-Hai Wang, Minglin Ma*, Islet encapsulation. Journal of Materials Chemistry B 6, 6705-6722 (2018).

20. Guang Yang, Yang Y Xu*, Zi D Zhang, Long-Hai Wang, Xue H He*, Qi J Zhang, Chun Y Hong*, Gang Zou*, Circularly polarized light triggered enantioselective thiol–ene polymerization reaction. Chemical Communications 53, 1735-1738 (2017).

19. Chen-Tao Xu, Guang Chen, Xuan Nie, Long-Hai Wang, Sheng-Gang Ding*, Ye-Zi You*, Low generation PAMAM-based nanomicelles as ROS-responsive gene vectors with enhanced transfection efficacy and reduced cytotoxicity in vitro. New Journal of Chemistry 41, 3273-3279 (2017).

18. Ting Wu, Long-Hai Wang, Shenggang Ding*, Ye-Zi You*, Fluorinated PEG‐polypeptide polyplex micelles have good serum‐resistance and low cytotoxicity for gene delivery. Macromolecular Bioscience 17, 1700114 (2017).

17. Long-Hai Wang, Ze Zhang, Tian-you Zeng, Lei Xia, Xuan Nie, Guang Chen, Ye-Zi You*, Responsive cationic polymer and cationic nanomicelle vectors for gene delivery. Acta Polymerica Sinica, 1883-1904 (2017).

16. Long-Hai Wang, Chun-yan Hong*, Synthesis and self-assembly of responsive branched polymers and their biomedical applications. Acta Polymerica Sinica, 200-213 (2017).

15. Long‐Hai Wang, De‐Cheng Wu, Hang‐Xun Xu, Ye‐Zi You*, High DNA‐binding affinity and gene‐transfection efficacy of bioreducible cationic nanomicelles with a fluorinated core. Angewandte Chemie International Edition 128, 765-769 (2016).

14. Long-Hai Wang, Ye-Zi You, Reactive oxygen species self-scavenging nanomicelles for highly efficient gene transfection. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. (AMER CHEMICAL SOC 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, 2016), vol. 252.

13. Long-Hai Wang*, Jun-Jie Yan, Ye-Zi You, A versatile method for encapsulating large-sized DNA into small-sized bioreducible nanocapsules. Nanomedicine: Nanotechnology, Biology and Medicine 2, 477-478 (2016).

12. Long-Hai Wang, Ting Wu, Ze Zhang, Ye-Zi You*, Unconventional transitions of poly (N-isopropylacrylamide) upon heating in the presence of multiple noncovalent interactions. Macromolecules 49, 362-366 (2016).

11. Long-Hai Wang, Ting Wu, De-Cheng Wu*, Ye-Zi You*, Bioreducible gene delivery vector capable of self-scavenging the intracellular-generated ROS exhibiting high gene transfection. ACS Applied Materials & Interfaces 8, 19238-19244 (2016).

10. Sheng-Gang Ding*, Lei Yu, Long-Hai Wang*, Lin-Ding Wang*, Zhi-Qiang Yu, Ye-Zi You, Self-assembling Janus dendritic polymer for gene delivery with low cytotoxicity and high gene transfection efficiency. Journal of Materials Chemistry B 4, 6462-6467 (2016).

9. Bo-Fei Cheng, Long-Hai Wang, Ye-Zi You*, Photoinduced electron transfer-reversible addition-fragmentation chain transfer (PET-RAFT) polymerization using titanium dioxide. Macromolecular Research 24, 811-815 (2016).

8. Lei Yu, Long-Hai Wang, Zong-Tao Hu, Ye-Zi You, De-Cheng Wu, Chun-Yan Hong*, Sequential Michael addition thiol–ene and radical-mediated thiol–ene reactions in one-pot produced sequence-ordered polymers. Polymer Chemistry 6, 1527-1532 (2015).

7. Long‐Hai Wang, Zi‐Dan Zhang, Chun‐Yan Hong, Xue‐Hao He, Wei You, Ye‐Zi You*, Anion–Dipole Interactions Make the Homopolymers Self‐Assemble into Multiple Nanostructures. Advanced Materials 27, 3202-3207 (2015).

6. Long-Hai Wang, Wu Ting, Ye-Zi You*, Anion–dipole interactions regulating the self-assembled nanostructures of polymers. Polymer Chemistry 6, 4972-4977 (2015).

5. Long‐Hai Wang, Sheng‐Gang Ding, Jun‐Jie Yan, Ye‐Zi You*, Bioreducible nanocapsules prepared from the self‐assembly of branched polymer in nanodroplet. Macromolecular Rapid Communications 35, 298-302 (2014).

4. Long-Hai Wang, Xiao-Man Xu, Chun-Yan Hong, De-Cheng Wu, Zhi-Qiang Yu, Ye-Zi You*, Biodegradable large compound vesicles with controlled size prepared via the self-assembly of branched polymers in nanodroplet templates. Chemical Communications 50, 9676-9678 (2014).

3. Long-Hai Wang, Sheng-Gang Ding, Jun-Jie Yan, Ye-Zi You*, A versatile method for encapsulating large-sized DNA into small-sized bioreducible nanocapsules. The Journal of Physical Chemistry B 118, 3893-3898 (2014).

2. Zhong-Kai Wang, Long-Hai Wang, Jiao-Tong Sun, Li-Fen Han, Chun-Yan Hong*, In situ generation of bioreducible and acid labile nanogels/microgels simply via adding water into the polymerization system. Polymer Chemistry 4, 1694-1699 (2013).

1. Jiao‐Tong Sun, Ji‐Gang Piao, Long‐Hai Wang, Mohsin Javed, Chun‐Yan Hong*, Cai‐Yuan Pan, One‐pot synthesis of redox‐responsive polymers‐coated mesoporous silica nanoparticles and their controlled drug release. Macromolecular Rapid Communications 34, 1387-1394 (2013).